Granger & Co Kings Cross will open on the ground floor of the Stanley Building on St Pancras Square late spring.
The 86-cover restaurant follows the opening of the chef's restaurants in Notting Hill and Clerkenwell and it will serve the same all-day offering inspired by Granger's 'far-flung travels'.
He said: “Kings Cross is the most connected place in London, and is set up for ideas - with Central St Martins, The Francis Crick Institute and Google as just a few of our neighbours. It’s a new creative hub in the most creative city of the world. I’m thrilled at the prospect of being part of it."