After launching at Stansted Airports' £80m redevelopment in March, the chain are expanding in the capital with sites opening on Fleet Street on 5 May, Neal Street on 8 May and Euston on 18 May.
A restaurant will also open at the Westfield White City development in July.
The brand confirmed summer openings were planned for Reading and Cambridge, and that it was currently scouting for locations around the UK.
“London remains critically important to us but we are looking for beautiful locations across the country. We hope to have news of further openings in the next few months,” a representative for Itsu told BigHospitality.
Speaking to one of BigHospitality's sister publications M&C Report last year, Itsu CEO Gerard Loughran said regional trading had been 'better than forecasted' and that plans were in place to roll out the brand nationwide.