The company, owned by Mark Wogan and Ry Jessup, will open the restaurant at the site formerly occupied by the Food Hall, next to Shoreditch Town Hall later this year.
Homeslice Shoreditch will follow the opening of a 70-cover restaurant in Fitzrovia in August.
“With the opening of our second site at 52 Wells Street imminent, securing our first east London site on Old Street marks the next step in our expansion plans,” said Wogan and Jessup. “Whilst we are currently focusing on launching our Wells Street site, we look forward to bringing Shoreditch a slice of the Homeslice experience later in 2015.”
Homeslice, which started out as a pop-up venture at Street Feast in east London, will continue to sell its core offering of 20” pizza available whole and by the slice, locally sourced beer, frizzante prosecco on tap and organic wine by the magnum at its Shoreditch site.