The 80-cover restaurant will offer what White calls ‘affordable glamour’, serving a selection of English and French dishes.
It will be the chef’s 13th steakhouse to open across the UK and Northern Ireland under a franchise agreement with Black and White Hospitality.
John Willcock, general manager at the Castle Hotel Windsor, said: “It’s wonderful news for our hotel guests and visiting diners that we have been able to gain such an authentic and exciting restaurant adjoining the hotel.
Dishes will include Entrecôte of Veal and Cambridge Burnt Cream and 28-day aged Native Breed Steaks.
White said: “My menus are designed to offer something for everybody, for every price point and budget, as the future of eating out is affordable glamour.”
Originally a Mecure property, the 108-room Castle Hotel Windsor was re-branded under Accor's high-end MGallery collection last year.
It is the first MGallery hotel to welcome a Steakhouse Bar & Grill, joining its sister Mercure sites in Leicester, Oxford, Stratford-upon-Avon and London Bridge which operate under the Marco's New York Italian Brand.