The chain is opening in Brighton in May and Tooting Market and Muswell Hill Broadway in June.
Plans are also in place for a 60-cover site opposite Kentish Town tube station and an 85-cover venue in Kilburn, North London.
David Sykes, at Franco Manca, said: “Response to our new Guildford restaurant has been overwhelmingly positive and we can’t wait to invite people to Kentish Town and Kilburn later this year.”
According to BigHospitality’s sister site MCA, Franco Manca has also secured sites in Putney High Street and will join Jason Atherton at the Nova Victoria development, bringing the chain’s portfolio to 27 restaurants by summer 2016.
Franco Manca began with a single restaurant in Brixton Market, expanding to ten sites across London in five years.
It was bought for £27.5m in 2015 by serial restaurateur and former Pizza Express CEO David Page.
Page told MCA earlier this year that a number of further sites are under negotiation however “we tread slowly – we sometimes sign sites but do not develop them immediately”.
Shelley Sandzer acted on behalf of Franco Manca in securing seven of its sites, including Kilburn and Kentish Town.