The restaurant on York Road in Battersea, has been closed since 1 January 2010 when the site was struck by a fire.
It has taken restaurateur Peter Ilic's business seven years to repair the site ready for re-opening under its new name.
While the restaurant is no longer called Little Bay, James Ditchfield, marketing manager for Little Bay and now TWID, said some of the original restaurant's features had been retained, such as its theatrical decor and tiered seating areas. Live Opera will also be performed at the site Mondays to Saturdays.
“It has been a long seven years. When the fire destroyed our restaurant in 2010, we were devastated. When we saw the extent of the damage and the years of work that had gone up in flames, it was hard not to become despondent," said Ditchfield.
"Quite honestly, the encouragement and support from our loyal customers and the local community in Battersea has been phenomenal. We hope that our new TWID restaurant will repay their kindness and become the heart of the local community once again.”
Features introduced at the new-look restaurant include a sharing menu featuring a range of meat, fish, vegetarian, vegan and raw dishes to choose from. The restaurant will also serve a range of raw vegan desserts made in-house.
TWID Live Music Bar and Restaurant remains part of Ilic's group of retsaurants which includes Little Bays in Brighton, Croydon and Kilburn.