The burger brand has secured a 60-cover site with counter dining space for eight close to Notting Hill Gate tube station.
The menu will feature all the group's classic burgers, alongside new dish ‘The Chicken Feast’ - a medley of fried chicken served with sauces and pickles on the side.
Drinks will include beers, cocktails and milkshakes, with flavours such as peanut butter malt; lemon cheesecake and triple chocolate.
It will be the eighth opening for Patty & Bun, which runs six restaurants across London and has a permanent residency at crazy golf bar Swingers LDN.
The group began as a London pop-up before launching its first permanent restaurant in Marylebone in 2013.