It comes after the Scottish-based company secured a £29m funding package to expand its English portfolio last year.
The Lampery restaurant has been created in partnership with hospitality company Concerto as part of an agreement to run food and beverage sites at three of Apex’s London hotels.
It offers a ‘Best of British’ menu with dishes including Lampery Pye, which Pepys’ – one of the areas’ famous former residents – described as a ‘most rare dish’ made with beef cheeks and prunes; and a thick pea and ham soup inspired by the 'peasouper' frogs that used to engulf London.
The restaurant is headed up by chef Francesco Zanchetta and also boasts a terrace area with a suspended foliage canopy and a bar.
It has opened as part of a nine-month revamp of the 209-room hotel, which first opened in 2005, with the overhaul of its public areas, meeting rooms and opening of a new spa.
Brian Tapson, general manager of the Apex City of London Hotel, says he hopes the food offering appeals ‘to locals as well as hotel guests’.
Apex is based in Edinburgh and operates six hotels in Scotland, three in London and one in Bath.