Chimis is the brainchild of chef Nicolas Modad and Federico Fugazza - the founder of Argentine street food stall Portena.
The pair met while working at Borough Market and used to socialise with their friend Mijal Lasus at Chilean restaurant El Vergel on Southwark Bridge road, which is popular with the expat community.
When the owner retired the group decided to take over the site to launch their first restaurant.
The 44-cover site will focus its menu around the parilla – an iron barbecue grill – with an emphasis on meat and fish.
Expect starters such as mollejas (sweetbreads with chimi lemon sauce); grilled Provolone; and empanadas.
Signature dishes will include grilled octopus with stuffed polenta, served with smoked paprika and salsa criolla; and Argentine rib eye and sirloin steak.
Chimis will open on 29 January.