The Evening Standard reports that the 124-year-old Parisian institution is taking a long lease on two storeys of a building in Fleet Street.
It will be the second London outpost for the renowned culinary school, which counts Mary Berry and Yotam Ottolenghi among its alumni.
Students will gain work experience in the “live” restaurant that will open on the site previously occupied by Sir Terence Conran’s Lutyens restaurant, which closed last year after Conran’s restaurant group fell into administration.
Consultants Duff & Phelps advised on the Le Cordon Bleu deal, which depended on planning permission being secured from the City of London Corporation, which happened this month.
The first Le Cordon Bleu cookery school opened in Paris in 1895, followed by a London outpost in Chelsea in 1931.
The school has since moved location within London a number of times, but eventually established its current premises on Bloomsbury Square in 2012.
There are now more than 50 Le Cordon Bleu schools in over 20 countries worldwide, which train over 20,000 students in culinary skills and hospitality management each year.