The group, which runs around 20 sites across Europe, will launch in the ground-floor of the former flagship YO! restaurant on Tottenham Court Road.
The central London site measures 1,956 sq ft and has an annual rent of £178,000, with a lease that runs until 2034.
Sushi Fabrique’s 90-cover restaurant will serve pan-Asian cuisine, with a focus on sushi.
A spokesman for the restaurant group says: “Sushi Fabrique brings a new level of sushi quality and freshness to the heart of London that has not been seen before, combining a superior level of food taste with a cosy and innovative atmosphere that will deliver a unique experience to the customer.”
Restaurant Property acted on the deal.