The boutique hoteliers have been confirmed as the anchor operator for Allied London’s overhaul of the grade II listed site, set to feature a ‘world class’ cocktail bar, spa, office area and hotel across five floors.
It will be The Zetter Group’s first hotel outside London and fourth overall.
Michael Benyan, director of The Zetter Group, said the site presented the ‘perfect opportunity’ for the brand’s first foray in to the north.
“London Road is an iconic building and a real gift for us as hoteliers,” he said.
“We want to preserve the existing beauty and magic of the building and use it to help create a unique experience for our guests.”
The group will be teaming up with Russel Sage Studios – the designers behind The Goring Hotel’s Royal Suite and several Gordon Ramsay restaurants – to create a ‘new benchmark for hospitality in Manchester’.
Michael Ingall, Allied London’s chief executive, said: “Russell Sage [is] someone I have admired for several years and is at the top of his game for interior design around the world. The building is in safe hands.
“Our task is now to craft and curate the rest of the development and we will be inviting certain hospitality operators to make proposals for the remaining spaces.”
The Zetter Group runs The Zetter Hotel and two Zetter Townhouse properties in London, as well as Bruno Loubet’s Grain Store restaurant in King’s Cross.
Allied London will submit a planning application for the project in Autumn 2016.