The chain says the exclusive partnership gives it greater flexibility in how it serves its coffee, and reflects a continued consumer appetite for the brand.
As well as coffee, customers will be able to order from a limited range of other hot and cold drinks; and a selection of food-to-go items, including pastries.
Last week Caffè Nero said it was moving forward with a takeaway-only trial of its operations, and would have more than 40 stores reopen by the end of the month.
All of its 800+ UK sites were closed in March as a result of the Coronavirus lockdown.
“Since we’ve opened some of our stores for takeaway, we’ve seen strong demand for our coffee," says Caffè Nero UK CEO Will Stratton-Morris.
"We want to be able to help those unable to visit one of our open stores enjoy our coffee without compromising the premium quality.
"I believe the partnership with UberEats allows us to do that and continue to as we open more stores.”
Caffè Nero says all reopened sites have implemented clear protocols to ensure employees and customers are kept safe; and are being staffed by a team of volunteers from its workforce who have requested to go back to work.